diff --git a/.github/workflows/pypi-release.yml b/.github/workflows/pypi-release.yml
index 0eb56a988..5a77a81e4 100644
--- a/.github/workflows/pypi-release.yml
+++ b/.github/workflows/pypi-release.yml
@@ -74,7 +74,10 @@ jobs:
       matrix:
         os: [macos-10.15, windows-2019]
         python-version: ['3.6', '3.7', '3.8', '3.9', '3.10']
-
+        exclude:
+        # pyobjc is not yet compatible with Python 3.10
+        - os: macos-10.15
+          python-version: '3.10'
     steps:
     - uses: actions/checkout@v2
     - name: Set up Python ${{ matrix.python-version }}